NMN Pure Powder

Support your NAD levels with NMN Pure Powderfrom Renue By Science, trusted by thousands ofcustomers as part of their daily wellness routine.Designed to promote cellular energy production,resilience, and vitality from the inside out.

99% Pure NMN

Third-Party Tested

Science-Driven Formulation

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Measured Success at Renue By Science

10 years moving the science forward as the global leader inNAD+product development. We build every formula around cellular energy and healthy aging using delivery methods that makeNAD+work better.

CUSTOMERS LOYALTY

Over 80% of our customers reorder.

YEARS LEADING

Leading NMN innovation for over 10 years.

COUNTRIES SERVED

Worldwide shipping to over 100 countries.

PRODUCTS SOLD

Over 1 million quality bottles sold worldwide.

RENUE BY SCIENCE PROMISE.

  • RESEARCH-BACKED

    Every ingredient is selected based on published clinical research in aging, cellular health, andNAD+metabolism. Our formulas follow the science, not trends, and we update them as new research becomes available.

  • CLEAN & SAFE

    Vegan, gluten-free, and non-GMO, with no fillers, artificial additives, or unnecessary ingredients in any formula. Every product is made to meet the same standards for safety and peace of mind.

  • THIRD-PARTY TESTED

    Every batch is tested for identity, purity, and potency by independent ISO- and cGMP-certified laboratories. Results are published so you can verify what's in the bottle before you buy.

  • MADE IN THE USA

    Manufactured in U.S. facilities that meet or exceed current Good Manufacturing Practice standards. Ingredients are third-party tested and sourced from trusted partners worldwide.

    NAD+ Declines With Age.Most Supplements Just Mask It.

    Your cells run on a molecule calledNAD+. The more you have, the better they perform. The less you have, the harder everything gets.

    By middle age, levels can fall by half, and your energy, recovery, and resilience fall with them.

    Most supplements just mask the decline.We work where the decline actually starts.

    We target the pathway. Not just the feeling.

    Meet Our Team of Experts

     

    “At the age of 63, I feel like I have the same strength and endurance from my 30s.“

    Bryan Nettles, Founder and CEO of Renue By Science, has a lifelong focus on nutrition, exercise, and longevity science. His personal health journey - recovering from prostate cancer - deepened his commitment to research and healthy aging. Driven to educate and empower others, he founded the company to make science-backed longevity solutions more accessible, helping people live longer, stronger lives at any stage.

    Bryan Nettles

    Founder & CEO

    Dr. Rebecca Crews holds a PhD in Biochemical and Molecular Nutrition from the Friedman School at Tufts University. Her research has spanned the Air Force Research Laboratory, Tufts, and Texas State, with published work on NMN supplementation, metabolic variability, and the science of NAD+ in healthy aging. At Renue By Science, she leads the research program and translates the latest longevity science into the formulas you find in our shop.


    Dr. Rebecca Crews
    Research Director

    Dr. Clark Driggers is the Chief Medical Advisor at Renue By Science, with a clinical focus on wellness, healthy aging, and regenerative medicine. He works at the intersection of clinical practice and longevity research, helping shape the science behind our formulas. His perspective grounds our work in what actually matters to patients in the real world: products that are safe, effective, and built on evidence.

    Dr. Clark Driggers

    Chief Medical Advisor

    Liposomal Delivery Means Greater Bioavailability.

    Liposomal delivery wraps sensitive ingredients like NMN and NR in phospholipids, the same fats that make up cell membranes, so they're protected during digestion and first-pass liver processing.

    The result: more of the active ingredients reach your cells, so a smaller dose can deliver significantly more support than standard formulas.

    What Are Liposomes and Why Do They Matter?

    Liposomes are microscopic spheres made of phospholipids: the same material that forms your cell membranes. When these dry, powdered phospholipids are mixed with water, they spontaneously organize into protective bubbles that can encapsulate nutrients and deliver them more effectively to your cells.

    Liposomes solve the bioavailability problem that many ingredients have. Many beneficial nutrients, especially polyphenols and other plant extracts, have absorption rates of less than 10%, and sometimes as low as 1% for molecules like resveratrol.¹ By protecting nutrients through digestion and facilitating their absorption, liposomal delivery can dramatically improve how much of each ingredient actually reaches your bloodstream and cells.

    The core benefits: what human studies show.

    • Bioavailability benefits with real numbers.

      Clinical trials demonstrate the difference liposomal delivery makes. A 2024 randomized controlled trial showed liposomal vitamin C produced higher plasma levels and maintained them longer compared to standard ascorbic acid.²For glutathione, both liposomal and non-liposomal oral forms have successfully raised glutathione status in humans, with liposomal forms outperforming the standard versions.³,⁴

    • Protection and stability.

      Liposomal encapsulation shields active ingredients from stomach acid (pH < 2), digestive enzymes, and oxidation - all factors that normally destroy sensitive nutrients before absorption.⁵The phospholipid bilayer maintains compound integrity during storage and through the digestive system.

    • Higher concentration per dose.

      Unlike simple capsules or tablets, liposomes can carry both water-soluble and fat-soluble nutrients together, which lets us create more complex formulas to suit various needs. This dual-loading capacity means more nutrient per particle reaches your system.⁶

    • Sustained, gradual release.

      Well-formulated liposomes can provide more gradual release of their contents, helping maintain steadier nutrient levels in your body rather than the spike-and-excrete pattern of conventional supplements.⁷

    • Better tolerability for sensitive digestion.

      Iron, a nutrient that is uncomfortable for many to take, provides the best-documented example: in clinical trials, liposomal iron caused significantly fewer gastrointestinal side effects than standard iron salts while maintaining effectiveness.⁸This improved tolerability extends to other nutrients that typically cause digestive upset, especially for those with sensitive digestion or older adults with more challenged gut health.

    • Flexible dosing with food.

      While meal timing still influences absorption to some degree, liposomal formulas reduce fed/fasted variability. The protective phospholipid layer means you have more flexibility in when you take your supplements.⁹

      How liposomal technology works.

      • THE PROTECTION PHASE

        When you swallow a supplement formulated with liposomes, the phospholipid bilayer acts as a molecular shield to protect the nutrients through digestion. Advanced formulations use specialized phospholipids to resist breakdown from bile salts and maintain stability through your entire digestive tract.¹⁰

      • CROSSING THE INTESTINAL BARRIER

        Something interesting happens when liposomes reach your intestines. The small liposome size, ideally 100-200 nanometers, allows them to navigate through intestinal mucus and trigger cellular uptake. The primary absorption route occurs through specialized M cells and enterocytes in your Peyer's patches via endocytosis, essentially being swallowed whole by intestinal cells.¹¹

        Even if some liposomes break down, the phospholipids help solubilize nutrients in your intestinal environment, creating additional absorption opportunities.

      • CELLULAR INTEGRATION

        After absorption, the phospholipid structure continues working. These lipids integrate with your cellular membranes more readily than free compounds, potentially improving delivery to target tissues. Plus, the phospholipids themselves, particularly phosphatidylcholine, provide nutritional benefits for cell membrane health, liver function, and cognitive performance.¹²,¹³

        Liposomal delivery for NAD+ precursors: NMN and NR.

        The challenge with NAD+ precursors.

        NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) face unique absorption challenges that make them ideal candidates for liposomal delivery. Research has identified that NMN is absorbed through the small intestine, including transporters like SLC12A8, with the CD73 enzyme facilitating uptake, but this process is pH-dependent and can be compromised by stomach acid.²³ Additionally, both compounds are rapidly metabolized: NMN can be broken down to nicotinamide by CD38 and other enzymes before reaching target tissues.²⁴

        Studies show that while oral NMN does raise NAD+ levels, the conversion efficiency varies significantly between individuals, likely due to differences in digestive conditions and enzyme activity.²⁵  NR faces similar challenges, with intestinal and hepatic metabolism converting much of it to nicotinamide before it can raise NAD+ in target tissues.²⁶

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